Hot ‘N’ Cold: Decoding Glioblastoma’s Complex Immune Landscape


An Integrated Preclinical Platform for GBM Immunotherapy Development

This white paper presents a strategic platform for leveraging patient-derived xenografts, humanized models, and predictive technologies to identify, optimize, and translate promising immunotherapeutic strategies. By integrating tumor mutational burden analysis, HLA profiling, and multi-modal endpoint assessment, researchers can design rational combination therapies that address GBM’s complex immune landscape with unprecedented precision.

 

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