--- title: "The Naked Science Behind Going Nude: A Case for Superior PDX Models in Preclinical Cancer Research" description: For cancer researchers advancing ADCs, cell therapies, and other targeted therapies, translational relevance of preclinical models matters more than ever. image: https://whitepapers.certisoncology.com/hubfs/2_NOGvsNudeMouse.webp --- [![CERTIS](https://whitepapers.certisoncology.com/hubfs/certis-lockup-horz-color.svg "CERTIS")](https://www.certisoncology.com/) - [Home](https://www.certisoncology.com/) - Drug Developers - [CertisAI™️](https://www.certisoncology.com/for-drug-developers/predictive-oncology-intelligence/) - [Cancer Models](https://www.certisoncology.com/for-drug-developers/cancer-models-preclinical-studies/) - [Custom Models](https://www.certisoncology.com/for-drug-developers/custom-model-development/) - [In Vitro/Ex Vivo](https://www.certisoncology.com/for-drug-developers/in-vitro-ex-vivo-pharmacology/) - [In Vivo](https://www.certisoncology.com/for-drug-developers/in-vivo-pharmacology/) - [Imaging/Endpoints](https://www.certisoncology.com/for-drug-developers/imaging-endpoint-analysis/) - [Immuno-Oncology](https://www.certisoncology.com/for-drug-developers/immuno-oncology/) - Oncologists - [Order YourPDX®](https://www.certisoncology.com/for-oncologists/order-yourpdx/) - [Clinical Research](https://www.certisoncology.com/for-oncologists/clinical-research/) - [Patient Education](https://www.certisoncology.com/for-oncologists/patient-education/) - About - [Mission, Vision & Values](https://www.certisoncology.com/about-us/mission-vision-values/) - [Team](https://www.certisoncology.com/about-us/our-team/) - [Our Story](https://www.certisoncology.com/about-us/our-story/) - [Careers](https://www.certisoncology.com/about-us/careers/) - [Company News](https://www.certisoncology.com/about-us/news/) - [Contact Us](https://www.certisoncology.com/contact-us/) - Resource Library - [Cancer Facts](https://www.certisoncology.com/resources/cancer-market-facts/) - [Clinical Results](https://www.certisoncology.com/resources/clinical-results/) - [Supporting Research](https://www.certisoncology.com/resources/supporting-research/) - [Media](https://www.certisoncology.com/resources/media/) - [White Papers](https://news.certisoncology.com/) - [Contact](https://www.certisoncology.com/contact-us/) [Database Login](https://oncointel.certisoncology.com) ![CTA\_KRAS-CertiScreen-824x424-1-720x424](https://whitepapers.certisoncology.com/hs-fs/hubfs/CTA_KRAS-CertiScreen-824x424-1-720x424.jpg?width=720&name=CTA_KRAS-CertiScreen-824x424-1-720x424.jpg "CTA_KRAS-CertiScreen-824x424-1-720x424") ### VALIDATE YOUR KRAS-TARGETING STRATEGY Combining Predictive AI + Advanced Cancer Models to Help Direct Oncology Drug Development and Clinic Research Studies. 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[LEARN MORE](https://www.certisoncology.com/kras-targeted-oncology-drug-development/) - [Cancer Facts](https://www.certisoncology.com/resources/cancer-market-facts/) - [Clinical Results](https://www.certisoncology.com/resources/clinical-results/) - [Supporting Research](https://www.certisoncology.com/resources/supporting-research/) - [Media](https://www.certisoncology.com/resources/media/) - [White Papers](https://news.certisoncology.com) # The Naked Science Behind Going Nude: A Case for Superior PDX Models in Preclinical Cancer Research For cancer researchers advancing ADCs, cell therapies, and other targeted therapies, translational relevance of preclinical models matters more than ever. By downloading this white paper, you’ll get a comprehensive guide to selecting the most effective PDX models and improving the translational relevance of your oncology research.   ![2\_NOGvsNudeMouse](https://whitepapers.certisoncology.com/hs-fs/hubfs/2_NOGvsNudeMouse.webp?width=348&height=223&name=2_NOGvsNudeMouse.webp)   ### Download White Paper [Back to Feed](https://blog.certisoncology.com) ### Share This ![Certis](https://whitepapers.certisoncology.com/hubfs/certis-logo-lockup-white.svg "Certis") 5626 Oberlin Drive, Suite 110 San Diego, CA 92121 Drug Development: 858-988-1033 Patients & Oncologists: 858-228-4110 Main: 858-952-1820 - #### Drug Developers - [CertisAI™](https://www.certisoncology.com/for-drug-developers/predictive-oncology-intelligence) - [Cancer Models](https://www.certisoncology.com/for-drug-developers/cancer-models-preclinical-studies) - [Custom Model Development](https://www.certisoncology.com/for-drug-developers/custom-model-development) - [In Vitro/Ex Vivo Pharmacology](https://www.certisoncology.com/for-drug-developers/in-vitro-ex-vivo-pharmacology) - [In Vivo Pharmacology](https://www.certisoncology.com/for-drug-developers/in-vivo-pharmacology) - [Imaging/Endpoint Analysis](https://www.certisoncology.com/for-drug-developers/imaging-endpoint-analysis) - [Immuno-Oncology](https://www.certisoncology.com/for-drug-developers/immuno-oncology/) - #### Oncologists - [Order YourPDX®](https://www.certisoncology.com/for-oncologists/order-yourpdx/) - [Clinical Research](https://www.certisoncology.com/for-oncologists/clinical-research/) - [Patient Education](https://www.certisoncology.com/for-oncologists/patient-education/) - #### Resource Library - [Cancer Facts](https://www.certisoncology.com/resources/cancer-market-facts) - [Clinical Results](https://www.certisoncology.com/resources/clinical-results) - [Supporting Research](https://www.certisoncology.com/resources/supporting-research) - [Media](https://www.certisoncology.com/resources/media) - [White Papers](https://news.certisoncology.com/) - #### About - [Mission, Vision & Values](https://www.certisoncology.com/about-us/mission-vision-values) - [Team](https://www.certisoncology.com/about-us/our-team) - [Our Story](https://www.certisoncology.com/about-us/our-story) - [Careers](https://www.certisoncology.com/about-us/careers) - [Company News](https://www.certisoncology.com/about-us/news/) - [Contact Us](https://www.certisoncology.com/contact-us) - [Login](https://oncointel.certisoncology.com) - [Privacy Policy](https://www.certisoncology.com/privacy-policy) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--facebook.svg)](https://www.facebook.com/CertisOncology) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--linkedin.svg)](https://www.linkedin.com/company/certis-oncology) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--twitter.svg)](https://twitter.com/CertisOncology) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--instagram.svg)](https://www.instagram.com/certis_oncology) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--youtube.svg)](https://www.youtube.com/channel/UCeX4_jh3RlNKxQxZ89_utjg) - [![](https://whitepapers.certisoncology.com/hubfs/social-media--blog.svg)](https://blog.certisoncology.com/) ![certis-footer-mouse](https://whitepapers.certisoncology.com/hubfs/certis-footer-mouse.svg "certis-footer-mouse") --- ©2024 Certis Oncology Solutions. 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